Injection Procedure Banner Square


Let's get in touch!


Let's get in touch!

Polynucleotide (PN) Treatment at a glance

Procedure Type

Procedure Type

Skin Booster

Skin Improvement


Skin appears younger, healthier, radiant
and glowing from within. Fight signs of ageing such as wrinkles, dull skin tone, loss of volume and age spots.
Improve overall skin health


*Results varies with individuals



Minimal downtime, but as with all injectables, there might be mild redness and swelling on the treated areas that will subside within 24 hours

Treated Areas


Procedure Time

Procedure Time

45 minutes

What is Polynucleotide (PN) Treatment?

Polynucleotide (PN), is a DNA fragment that is extracted from Italian Trout using HPT™ technology that are bio-compatible with human DNA and is known to improve overall skin health.

What can PN Treatment help with?

  • Fighting the signs of ageing such as wrinkles, dull skin tone, loss of skin volume, and age spots. 
  • Repair damaged skin problems like acne scars, hyperpigmentation, enlarged pores, and overly sensitive skin. 

Here at EHA Clinic, we provide this treatment with PLINEST and PLINEST fast.

How does Polynucleotide (PN) Treatment work?


This treatment is clinically proven to improve overall skin health from within by:

  1. Promoting bio-revitalisation to fight signs of ageing
  2. Regenerating fibroblast and collagen to repair damaged skin
  3. Improving hydration and elasticity
  4. Restoring glowing skin radiance and youthfulness

What is PLINEST?

PLINEST & PLINEST fast are known as the originators of Polynucleotides (PN) skin boosters developed with HPT™ technology, with excellent safety profile certified by EU CE mark since 2005. 

This treatment is not a dermal filler. It does not provide volumising effects like a dermal filler, instead it uses Polynucleotides to rejuvenate the skin by providing hydration, elasticity and anti-ageing benefits. 

Your Polynucleotide (PN) experience at EHA Clinic

The treatment area is cleaned and numbing cream is applied.

The doctor then carefully injects the Polynucleotide skinbooster at the pre-marked area.

Multiple small bumps can be expected right after treatment. The bumps should disappear within the next few days, and there should be no problems resuming normal activities.

Treatment time is typically 30 – 60 minutes, depending on the site of treatment.

Meet your EHA Clinic Doctors

Dr. Elias Tam Portrait Rectangle

Dr. Elias Tam, the Doctor Trainer

Dr. Elias Tam, with over 30 years in medicine, leads EHA Clinic, focusing on advancing technical standards in aesthetic medicine. He holds the position of Clinical Lecturer at University College London, a distinctive honour as the sole aesthetic medical doctor and the only doctor from Asia in this role. Throughout his many years as an aesthetic doctor, Dr. Tam has held multiple hands-on training sessions and seminars, sharing his vast knowledge and expertise with aspiring doctors in the field.

Under his guidance, EHA Clinic offers a safe and comprehensive range of aesthetic treatments for the face, body, and hair; including FDA-approved procedures such as hair transplants, non-surgical face-lifting, body sculpting, fillers and other injectable treatments.

Dr. Jane Pang Portrait Rectangle

Dr. Jane Pang

Dr. Jane Pang holds a Bachelor of Medicine and Bachelor of Surgery from the University of Malaya and is registered with the Singapore Medical Council (SMC). With special interest in Women’s Health, and a wealth of expertise in a variety of aesthetic treatments.

Not only that, Dr. Pang’s diverse medical background in General Medicine, Orthopaedic Surgery, and Paediatric Medicine further enriches her practice at EHA Clinic.

Dr. Jane Pang Portrait Rectangle

What to expect after procedure

After the first session, visible facial firmness due to improved skin hydration, that will tighten up and lift up your skin. 

After the second session, visible skin smoothness because the scars, wrinkles and fine lines are flattened and lightened. You may also notice enhanced, natural glowing skin radiance. 

After third session, visible boosted skin volume
and firmer skin texture.

*Results may vary with individuals

Post-treatment care

Visible bumps, redness and swelling on the skin
can be observed after treatment, the effects are temporary and lasts only a few hours. 

It is recommended to repeat the protocol after 6–9 months. The results may vary depending on
individual lifestyle and skin. 

Can PN Treatment be combined with other aesthetic treatments?

Yes, PN treatments can be combined with other aesthetic treatments such as laser, filler, peeling, Botulinum Toxin, and needling procedures, with 2 to 3 weeks apart between the treatments. 

Who is suitable for PN Treatment?

This treatment is suitable for both males and females who want to prevent ageing of the skin and maintain their skin’s youthful appearance.
As it is not a dermal filler, it does not augment the shape of your face or features. Instead, it provides an overall subtle and natural improvement.

Interested in PN Treatment?

Start your journey to a clearer skin today with a non-obligatory consultation