Pigmentation assessment & treatment
Target Pigmentation At Different Depths With Synergy Fade
A combination pigmentation protocol using multiple laser wavelengths, topical stem-cell-derived exosomes and iontophoresis within one treatment session.
Treatment begins with a clinical assessment to determine the characteristics of your pigmentation and whether Synergy Fade may be suitable for you.
Multi-Wavelength Laser
Topical Exosome Application
Iontophoresis
Enquire About Synergy Fade
Pigmentation assessment & treatment
Concerned About Uneven Pigmentation?
Synergy Fade may be considered for different pigmentation concerns following clinical assessment.
Melasma
Patchy areas of pigmentation that commonly appear across areas such as the cheeks, forehead and upper lip.
Post-Acne Marks
Areas of darker pigmentation that may remain following acne or skin inflammation.
Sun Spots
Areas of pigmentation associated with cumulative sun exposure.
Freckles
Small areas of concentrated pigmentation that may become more noticeable with sun exposure.
The Synergy Fade protocol
Three Components. One Pigmentation Protocol.
Three Components.
One Pigmentation Protocol.
Synergy Fade combines three treatment components within the same session, with each serving a different role within the protocol.
Multiple Laser Wavelengths
Different laser and light-based technologies work at different depths within the skin. Depending on your clinical assessment, Pico Laser, IPL, and long-pulse laser may be selected and combined as part of the treatment protocol.
Topical Exosome Application
A stem-cell-derived exosome formulation is applied topically immediately following the laser component, while the skin is more permeable. Topical application. Not injected.
Iontophoresis
A mild electrical current is used to support the absorption of the topical formulation into the skin.
MULTI-WAVELENGTH LASER → TOPICAL EXOSOME APPLICATION → IONTOPHORESIS
$388 per session
A depth-led approach
Pigmentation Can Exist At Different Depths
Not all visible pigmentation sits at the same level within the skin. Different laser wavelengths penetrate to different depths, which is why Synergy Fade may incorporate 2–3 wavelengths depending on the pigmentation identified during your assessment.
Different Pigmentation Depths
Pigmentation may be present at different levels within the skin.
Multiple Wavelengths
Different wavelengths penetrate to different depths.
Assessment-Led Selection
The treatment approach is determined based on clinical assessment.
The number and type of laser wavelengths used will depend on clinical assessment.
Your care team
Your Synergy Fade Treatment With Dr Marie Li
Dr Marie Li
Aesthetic Doctor, EHA Clinic
Synergy Fade is performed by Dr Marie Li at EHA Clinic. Your treatment begins with a clinical assessment to understand your pigmentation concerns before determining whether Synergy Fade may be suitable for you.
Dr Marie holds an MBBS from the University of Western Australia, a Diploma in Aesthetic Medicine, and a Graduate Diploma in Family Medicine. She is registered with the Singapore Medical Council and holds ADEG accreditation.
Her focus on pigmentation goes beyond the clinical and she has navigated a personal experience with pigmentation herself, and understands firsthand what it means to live with a condition that can be difficult to treat and easy to mismanage. That perspective shapes how she connects with patients facing similar concerns.
Where appropriate, the treatment approach and selection of laser wavelengths are determined based on the clinical assessment.
Approved medical qualifications
MBBS (University of Western Australia), Diploma in Aesthetic Medicine, Graduate Diploma in Family Medicine, Singapore Medical Council registration, ADEG accreditation
Approved relevant credentials / memberships
Society of Aesthetic Medicine Singapore,
American Academy of Aesthetic Medicine
Your appointment
What To Expect
01 Clinical Assessment
Your pigmentation concerns are assessed to determine treatment suitability and approach.
02 Synergy Fade Treatment
Where suitable, the selected laser wavelengths, topical exosome application and iontophoresis are performed within the treatment session.
03 Aftercare
Your doctor will advise on appropriate aftercare following treatment.
04 Ongoing Management
Pigmentation changes generally occur gradually. Depending on your pigmentation concern and individual response, further treatment or ongoing management may be discussed.
Pigmentation treatment is not an overnight process.
Certain pigmentation concerns, including melasma, can recur. Sun protection and appropriate ongoing management remain important. Individual responses to treatment vary.
Helpful information
Frequently Asked Questions
Not all visible pigmentation sits at the same level within the skin. Different laser wavelengths penetrate to different depths, which is why Synergy Fade may incorporate 2–3 wavelengths depending on the pigmentation identified during your assessment.
Synergy Fade may be considered for pigmentation concerns including melasma, post-inflammatory hyperpigmentation, post-acne marks, sun spots and freckles. Treatment suitability is determined following clinical assessment.
Synergy Fade may be considered for individuals with melasma following clinical assessment. Melasma can be influenced by multiple factors and may recur, so an appropriate management approach will depend on the individual.
No. The stem-cell-derived exosome formulation used during Synergy Fade is applied topically to the skin.
Different laser wavelengths penetrate to different depths within the skin. Depending on the pigmentation identified during assessment, 2–3 wavelengths may be selected.
The number of sessions varies depending on the individual, pigmentation concern and response to treatment. Your doctor will discuss an appropriate treatment approach following assessment.
Start with an assessment
Not Sure Which Pigmentation Treatment Is Suitable For You?
Speak with the EHA Clinic team to find out whether Synergy Fade may be appropriate for your pigmentation concerns.
Enquire About Synergy Fade
Submit your details and our team will get in touch with you regarding your enquiry.
Treatment suitability and treatment approach are subject to clinical assessment. Individual responses to treatment may vary.
Copyright 2026 © EHA PTE LTD
Clinical assessment is required before treatment suitability can be determined.
Copyright 2026 © EHA PTE LTD